PMC

Histological features of germ-cell tumor (seminoma) with somatic malignant transformation (spindle cell sarcoma) (A) Classic seminoma (upper right corner) associated with spindle cell sarcoma (lower left corner), (H&E 200x). (B) in situ germ cell neoplasia (upper right corner) admixed with somatic spindle cell sarcoma (lower left corner), (H&E 200x). (C) Metastatic spindle cell sarcoma within the spermatic cord (H&E 200x). (D) The same field of picture C shows high proliferative Ki67 index (DAB 200x).

Macroscopic and pathological findings of the resected spermatic cord tumor.aMacroscopic view of the resected specimen demonstrating a 10-cm multinodular mass.bLoupe image of the tumor without continuity to testis.cPathological examination revealed proliferation of large polygonal cells.dThe partial presence of rhabdoid cells with desmin positivity.

Showing CECT picture of a sarcoma (fat is not delineated nicely).

Distribution of histopathology (n = 53; various malignant histopathologies: adenocarcinoma of the rete testis, liposarcoma of the spermatic cord, myeloid sarcoma of the testis and pancreatic analogous solid-pseudopapillary neoplasm of the testis; various benign histopathologies: infection (n = 4), residual fibrosis after chemotherapeutically pretreated teratoma (n = 1), normal testicular tissue (n = 5), sclerosis/fibrosis (n = 2), Sertoli cell hyperplasia/tumor (n = 2), Leydig cell hyperplasia (n = 1), atrophy (n = 4), hematoma (n = 1) and St. p. testicular torsion (n = 1)).